Q: Does John Simm look like Thom Yorke?/Does Thom Yorke look like John Simm?
A: Sometimes. Partly. Occasionally astonishingly so. Sometimes not at all.

Nose and eyebrows: almost identical (except Yorke's eyebrows are a bit straighter, whereas Simm's are a bit more curved.)
Facial shape: Yorke's is narrower. ETA: And longer. Look at that chin.
Mouth: Yorke's is a bit wider. Simm's lips are (possibly, a bit) fuller. Kinda hard to compare with the picture on the left, though, in which Yorke's lips were practically invisible due to lighting/colour issues. I had to play around with the colours to make them a bit more visible.
Hairline: Can't be compared in these pics, as Simm's is cut off, but other pictures show it's similar. Or was similar. They may be aging differently. Difficult to tell with Yorke and his various cases of Rock Star Hair.
Eyes: Hm.
Wouldn't be surprised to find out they share an ancestor, a few generations back.
Of course, this is only a frontal shot.Clearly I need to do this for a profile shot, too.
Clearly I need to start preparing my seminar.
A: Sometimes. Partly. Occasionally astonishingly so. Sometimes not at all.

Nose and eyebrows: almost identical (except Yorke's eyebrows are a bit straighter, whereas Simm's are a bit more curved.)
Facial shape: Yorke's is narrower. ETA: And longer. Look at that chin.
Mouth: Yorke's is a bit wider. Simm's lips are (possibly, a bit) fuller. Kinda hard to compare with the picture on the left, though, in which Yorke's lips were practically invisible due to lighting/colour issues. I had to play around with the colours to make them a bit more visible.
Hairline: Can't be compared in these pics, as Simm's is cut off, but other pictures show it's similar. Or was similar. They may be aging differently. Difficult to tell with Yorke and his various cases of Rock Star Hair.
Eyes: Hm.
Wouldn't be surprised to find out they share an ancestor, a few generations back.
Of course, this is only a frontal shot.
Clearly I need to start preparing my seminar.